Abstract #3920

Slice-by-slice B0 Shimming for high-resolution diffusion MRI with an ultra-high performance head-only gradient

Sherry S. Huang¹, Seung-Kyung Lee², Robert Shih^3,4, Raymond Huang⁵, Daniel Cornfeld⁶, Jerome Maller⁷, Jennifer A. Mcnab⁸, Thomas K.F. Foo², and Ante Zhu²

¹Science and Technology Office, GE HealthCare, Royal Oak, MI, United States, ²Technology and Innovation Center, GE HealthCare, Niskayuna, NY, United States, ³Uniformed Services University of the Health Sciences, Bethesda, MD, United States, ⁴Walter Reed National Military Medical Center, Bethesda, MD, United States, ⁵Brigham and Women’s Hospital, Boston, MA, United States, ⁶Mātai Medical Research Institutes, Gisborne, New Zealand, ⁷GE HealthCare, Melbourne, Australia, ⁸Stanford University, Stanford, CA, United States

Synopsis

Keywords: Diffusion Acquisition, Shims, Diffusion

Motivation: High-resolution diffusion MRI in high-gradient head-only systems, which is promising for advancing our understanding of human brain microstructure, is still prone to distortion from B0 field inhomogeneity.

Goal(s): To reduce B0 field inhomogeneity for improved image quality of high-resolution diffusion MRI.

Approach: Dynamic slice-by-slice B0 shimming of 0^th and 1^st order was implemented in diffusion MRI.

Results: Preliminary results showed reduced image shift and distortion of slices at different locations in axial b=0 s/mm² echo planar image with 1-mm isotropic resolution with dynamic slice-dependent B0 shimming, demonstrating the potential of high image quality of high-resolution diffusion MRI for brain microstructure imaging.

Impact: Neuroimaging scientists and MR physicists, who use high-resolution diffusion MRI for studying brain circuits, connectivity, and microstructure, can benefit from improved image quality with reduced distortion from dynamic slice-by-slice B0 shimming technique in high-performance gradient MRI systems.

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