Keywords: Small Animals, Animals, cirrhosis,Cirrhotic cardiomyopathy
Motivation: As an important complication of cirrhosis, early diagnosis of cirrhotic cardiomyopathy (CCM) has a profound impact on prognosis of patients.
Goal(s): Find in myocardial strain parameters beyond global longitudinal strain (GLS) that are relevant for early diagnosis of CCM.
Approach: The heart and liver were scanned with magnetic resonance and multiple strain parameters were obtained from cardiac magnetic resonance to evaluate their potential diagnostic value for CCM and correlation with liver lesions.
Results: Compared with GLS and left ventricular ejection fraction , short-axis peak diastolic radial strain rate (PDRSR-S) has an earlier time to change, better diagnostic performance, and better correlation with liver lesions.
Impact: We discoveries a myocardial strain parameter , short-axis peak diastolic radial strain rate, who showed excellent potential in the early diagnosis of cirrhotic cardiomyopathy. The discovery laid the foundation for future research and clinical applications.
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