Keywords: Large Animals, Nonhuman Primates, Animals, CMR, pig
Motivation: Domestic pigs are frequently used as experimental animals for cardiovascular research but are subject to somatic growth.
Goal(s): To investigate the relationship of cardiac functional and volumetric parameters with animal somatic growth.
Approach: In this retrospective CMR study in 58 female Swiss large white pigs, we correlate functional volumetric and dimensional CMR parameters to animal weight.
Results: : Left ventricular mass, left and right ventricular volumes and stroke volumes correlate with animal weight. Weight-independent parameters were left and right ejection fractions. Our findings match values found in humans.
Impact: We provide a regression analysis of clinical functional, volumetric and dimensional CMR parameters for experimental planning and refinement of animal experiments in pigs and illustrate healthy parameter ranges.
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