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Abstract #3988

A comparative study of dynamic contrast-enhanced MRI and voxel-incoherent motion in evaluating microcirculation in rectal cancer

Jie Yuan1, Mengxiao Liu2, Wenli Tan1, and Songhua Zhan1
1Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China, 2Diagnostic Imaging, Siemens Healthineers Ltd, Shanghai, China

Synopsis

Keywords: Cancer, Digestive

Motivation: For the preoperative assessment of rectal cancer microcirculation use DCE ang IVIM.

Goal(s): To analyze the correlation between rectal cancer microvascular density, as indicated by CD34 immunohistochemistry, and quantitative parameters obtained from DCE and IVIM MRI.

Approach: Assess the correlation between quantitative imaging parameters from DCE and IVIM, and microvascular density.

Results: Significant differences in Ktrans and D values among different degrees of rectal cancer differentiation; furthermore, Ktrans, Kep, and D* values exhibited significant correlations with rectal cancer microvascular density, while Ve, D, and f did not show significant correlations.

Impact: The validation of the utility of non-invasive MRI techniques, particularly DCE and IVIM, assesses rectal cancer microcirculation, which can enhance early diagnosis and treatment planning for patients, ultimately improving the prognosis and management of rectal cancer.

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