Keywords: RF Arrays & Systems, RF Arrays & Systems
Motivation: Ex-vivo brain DWI with long scan times poses the problem of temperature-related drift of diffusion measurement results.
Goal(s): The construction of a 64-channel ex-vivo brain coil with time-course temperature stabilization for obtaining accurate DWI measurements.
Approach: Combining a newly developed high-density ex-vivo brain coil array with a forced-air cooling system and a multi-channel temperature recording.
Results: The air circulation system was able to maintain the ambient temperature of the coil and, thus, stabilizing the mean diffusivity values over repeated lengthy scans. Without cooling, a drift of the mean diffusivity was overserved, peaking at a 35%-offset at approximately 11 hours.
Impact: Temperature-stabilized post-mortem brain samples for diffusion MRI in combination with a dedicated large channel count ex-vivo brain coil improves image quality in terms of achievable SNR and greatly reduced temperature-induced diffusivity shifts.
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