Keywords: RF Pulse Design & Fields, RF Pulse Design & Fields, Multiphoton, SMS, SAR, PINS, MultiPINS
Motivation: Elevated specific absorption rate (SAR) levels pose a significant challenge for simultaneous multislice (SMS) imaging especially at high field strengths.
Goal(s): Multiphoton excitation has recently been proposed for reduced-SAR SMS applications. We aim to evaluate the SAR benefit of multiphoton SMS imaging compared to PINS and MultiPINS.
Approach: We show how pulse parameters affect the efficiencies of multiphoton SMS, PINS, and MultiPINS compared to conventional SMS through simple calculations and simulations. Additionally, we implement a multiphoton SMS spin-echo sequence in vivo at 3T.
Results: Multiphoton SMS is more SAR-efficient than PINS and MultiPINS for short pulse durations and thin slices under slew-rate constraints.
Impact: Multiphoton excitation makes short pulse durations and thin slices possible for SMS applications under SAR and slew-rate constraints. This subsequently enables the acquisition of high-quality imaging data for both scientific and medical purposes while reducing scan times.
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