Keywords: Liver, Liver
Motivation: The prognostic value of component percentage in combined hepatocellular carcinoma-cholangiocarcinoma (cHCC-CCA) was verified, but the identification of percentage of each component relies on extensive tumor sampling.
Goal(s): Therefore, the aim of this study was to investigate if MRI-based habitat imaging helps to predict component percentage in cHCC-CCA preoperatively,
Approach: and to further verify the biologic underpinnings of habitat imaging in cHCC-CCA by analyzing RNA sequencing data.
Results: We found that preoperative prediction of HCC percentage in patients with cHCC-CCA can be achieved using an MRI-based habitat imaging model, which was also associated with signaling pathways regulating cell migration and tumor metastasis.
Impact: We achieved prediction of HCC percentage through an MRI-based habitat imaging model, and revealed the biologic underpinnings of habitat imaging, that is, habitat imaging may identify patients at risk of metastasis. These results may guide individual management in cHCC-CCA patients.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords