Keywords: Liver, Liver, Hepatocellular Carcinomas resection
Motivation: Individualized selection between wide (≥1 cm) and narrow (<1 cm) resection margins may help improve the postoperative survivals of hepatocellular carcinoma (HCC).
Goal(s): To develop an MRI-based model to support the selection between narrow and wide resection margins based on the prediction of postoperative early recurrence-free survival (RFS, ≤2 years) in patients with single HCC.
Approach: In patients with narrow resection margins, a predictive score (named “MARGIN”) was developed for early RFS rate with Cox regression analyses.
Results: Improved early RFS rate was observed for wide resection margins for the MARGIN-predicted high-risk patients.
Impact: In patients with single HCC, the MARGIN score may serve as a promising decision-making too to inform the need for wide resection margins.
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