Keywords: Liver, Liver
Motivation: UTE-MT can non-invasively quantify the macromolecular content changes of short T2 tissues, which has the potential to assess non-alcoholic fatty liver disease (NAFLD).
Goal(s): To utilize the quantitative UTE-MT technique to assess NAFLD.
Approach: Sixteen mice (8 control mice and 8 mice with NAFLD) underwent liver scans using UTE-MT sequence on a 3T MRI scanner.
Results: The liver UTE-MTR values of mice in the NAFLD group were significantly lower than those in the normal group. High AUC values (AUC=0.955) obtained from the ROC analysis demonstrate that the UTE-MTR could differentiate the normal and NAFLD cohorts.
Impact: The UTE-MTR can detect the macromolecular changes in the liver. Liver UTE-MTR may serve as a promising imaging biomarker to assess NAFLD.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords