Keywords: Sparse & Low-Rank Models, DSC & DCE Perfusion, Pancreas, Abdomen, Quantitative Imaging, Image Reconstruction, Free-breathing
Motivation: Efficient image models are needed to enable low-dose, free-breathing quantitative dynamic contrast-enhanced (DCE) imaging in the abdomen.
Goal(s): Integrate non-rigid motion compensation (MoCo) into the MR Multitasking framework and evaluate its impact on low-dose, free-breathing abdominal DCE.
Approach: Non-rigid MoCo was incorporated into MR Multitasking by directly applying motion fields to eigenimages. This was tested on n=5 healthy volunteers who received 0.02 mmol/kg Gd, only 20% of the standard dose.
Results: Non-rigid MoCo of eigenimages was compatible with MR Multitasking. MoCo more efficiently modeled respiratory motion and minimized intra-bin motion, demonstrating potential for improved DCE quantification.
Impact: Non-rigid motion compensation reduces intra-bin respiratory motion in low-dose free-breathing, whole-abdomen quantitative dynamic contrast-enhanced (DCE) MR Multitasking. Low-dose quantitative DCE may benefit longitudinal monitoring of neoadjuvant treatment in patients with borderline resectable/locally advanced pancreatic ductal adenocarcinoma.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords