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Abstract #4206

Denoise of Dynamic Sodium MRI imaging at 3T using MPPCA

Abhipsha Das1,2,3, Ying-Chia Lin1,2, Jelle Veraart1,2, and Yongxian Qian1,2
1Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 2Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 3Courant Institute of Mathematical Sciences, New York University, New York, NY, United States

Synopsis

Keywords: Other Neurodegeneration, Neuro, Denoise, Sodium MRI, MP-PCA

Motivation: Sodium MRI, a valuable imaging modality for various clinical applications, faces challenges related to signal-to-noise ratio (SNR). This study aims to enhance sodium MRI image quality through innovative denoising techniques.

Goal(s): Evaluate and compare novel denoising methods to improve sodium MRI quality and diagnostic potential.

Approach: The study assesses denoising techniques in sodium MRI data, utilizing a 3T clinical scanner and a unique denoising algorithm MPPCA with reduced input requirements. Evaluation metrics include residual distributions, SNR and mean-square-error comparisons.

Results: MPPCA consistently outperforms other methods, showing its effectiveness in reducing noise and maintaining data fidelity.

Impact: The study demonstrates the potential of MPPCA as a powerful tool for enhancing sodium imaging, with broader implications for healthcare diagnostics and research.

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Keywords