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Abstract #4243

Effects of sleep quality on static functional connectivity between white and gray matter in human brain

Shuang Hu1, Yuhan Zhou2, yuanyuan Qin1, and Wenzhen Zhu1
1Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan,China, China, 2Department of Occupational and Environmental Health, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan,China, China

Synopsis

Keywords: Functional Connectivity, Brain Connectivity

Motivation: Sleep, accounting for one-third of human life, is a universal biological function, and sleep disorders may adversely affect health and well-being.

Goal(s): Sleep disorder affect functional structure of brain and the effect on white matter functional connectivity is unclear.

Approach: we divided white and gray matter into 48 and 82 regions and calculated Pearson's correlation coefficients between the regions to explore the functional connectivity of white and gray matter affected by sleep quality.

Results: The left secondary visual cortex and the dorsal anterior cingulate cortex were significantly correlated with the sleep quality.

Impact: Which suggests that V2 and dACC, as well as the white matter fiber tracts connected to these two brain regions, need more attention in the diagnosis and treatment of sleep disorders.

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