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Abstract #4275

Efficient spatial regularisation of dictionary matching using discrete Markov random fields

Donovan Tripp1, Karl P Kunze1,2, Claudia Prieto1,3,4, René Botnar1,3,4,5, and Radhouene Neji1
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Camberley, United Kingdom, 3School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 4Millennium Institute for Intelligent Healthcare Engineering, Santiago, Chile, 5Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile

Synopsis

Keywords: Image Reconstruction, Image Reconstruction

Motivation: Dictionary matching, used extensively in quantitative MRI, is resistant to standard approaches to spatial regularisation due to its discrete nature.

Goal(s): Demonstrate the feasibilty of efficient spatial regularisation of parameter maps produced via dictionary matching, in this work using total variation (TV) regularisation.

Approach: Spatially regularised dictionary matching was formulated as an optimisation on a discrete Markov random field, and the result optimisation problem solved using a primal-dual strategy, with the efficient iterative solver FastPD.

Results: TV regularisation improved apparent quality of parameter maps in phantoms and in vivo.

Impact: The proposed technique offers a means to improve the quality of parameter maps from any quantitative framework employing dictionary matching, covering a wide range of possible anatomies and clinical applications.

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Keywords