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Abstract #4285

Propeller Diffusion-Weighted Imaging of Endometrial Cancer with Deep Learning Reconstruction

Priya R Bhosale1, Xinzeng Wang2, Revathy B Iyer1, Arnaud Guidon3, Ken-Pin Hwang1, and Jingfei Ma1
1MD Anderson Cancer Center, Houston, TX, United States, 2GE Healthcare, Houston, TX, United States, 3GE Healthcare, Boston, MA, United States

Synopsis

Keywords: Pelvis, Cancer

Motivation: Diffusion-weighted imaging (DWI) is used in endometrial cancer imaging for improved specificity and accuracy in determining the depth of myometrial invasion compared to T2-weighted imaging alone. However, conventional echo planar imaging based DWI, including reduced FOV EPI, is prone to artifacts from field inhomogeneity in the area of endometria and from peristalsis.

Goal(s): To improve the diffusion-weighted imaging of endometrial cancer

Approach: Propeller DWI is robust to field inhomogeneity and motion. Deep learning (DL) reconstruction is used to mitigate its SNR deficiency and overcome the need for long scan time.

Results: DL DW-PROPELLER improved the SNR and in-plane resolution of the conventional DW-PROPELLER

Impact: DL DW-PROPELLER improved the SNR and in-plane resolution of the conventional DW-PROPELLER, enabling body DW-PROPELLER in clinically feasible scan time. Compared to the rFOV DW-EPI, DL DW-PROPELLER significantly improves the geometric accuracy and the readability of high b-value images.

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