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Abstract #4335

Exploring latent space representations of T1/T2 relaxation, cardiac motion, and respiratory motion for multidimensional quantitative CMR

Xinguo Fang1,2,3, Tianle Cao1,2,3, and Anthony G. Christodoulou1,2,3
1Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States, 2Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 3Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States

Synopsis

Keywords: Signal Representations, Cardiovascular, Cardiac binning, respiratory binning, motion identification, variational autoencoder (VAE), multidimensional quantitative imaging

Motivation: Respiratory and cardiac motion identification is challenging with changing contrast weightings for self-gated multidimensional techniques like MR multitasking.

Goal(s): To guide VAE latent vector constraints design for representing relaxation and motion.

Approach: We evaluated VAE representational fidelity for 16 combinations of constraints on T1/T2 relaxation, cardiac, and respiratory latent dimensions.

Results: The results demonstrate that nonlinear T1/T2 relaxation representations and cardiac phase representations improve VAE performance.

Impact: Latent space design is important for VAE learning in multidimensional cardiac imaging, suggesting avenues for better self-gated cardiac and respiratory binning.

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Keywords