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Abstract #4343

Improving Outcomes in Deep Brain Stimulation: A Comparative Study of 7T versus 3T Targeting

Erik Middlebrooks1, Xiangzhi Zhou1, Shengzhen Tao1, Elena Greco1, Lela Okromelidze1, Vishal Patel1, and Sanjeet Grewal1
1Mayo Clinic, Jacksonville, FL, United States

Synopsis

Keywords: Other Neurodegeneration, High-Field MRI, Surgical Planning, Essential Tremor, Deep Brain Stimulation, Neuromodulation

Motivation: 7T MRI offers improved image quality for deep brain stimulation (DBS) targeting, but greater distortion and artifacts that could lead to inaccurate targeting.

Goal(s): Our goal was to compare outcomes in DBS for essential tremor between patients targeted using 3T versus 7T MRI.

Approach: Retrospective comparison of DBS patients with ET was performed with patients targeted using 3T versus 7T MRI. We assessed differences in tremor improvement, adverse events, and electrode positioning.

Results: ET DBS patients targeted with 7T had significantly greater tremor control compared to 3T, as well as lower stimulation currents and improved electrode precision.

Impact: Despite challenges of 7T MRI in surgical planning, outcomes in DBS for ET were improved by use of 7T MRI versus 3T MRI, including better tremor control, reduced stimulation currents, and greater precision.

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