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Abstract #4435

Distortion-free Diffusion Imaging Using BUDA-gSlider on the Connectome 2.0 System

Jaejin Cho1,2,3, Qiang Liu2,4, Yohan Jun1,2, Shohei Fujita1,2, Xingwang Yong1,2,5, Tae Hyung Kim6, Mirsad Mahmutovic7, Boris Keil7,8, Camilo Jaimes2,3,9, Michael S Gee2,3,9, Susie Huang1,2,10, and Berkin Bilgic1,2,10
1Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 2Harvard Medical School, Boston, MA, United States, 3Pediatric Imaging Research Center, Massachusetts General Hospital, Boston, MA, United States, 4Brigham and Women's Hospital, Boston, MA, United States, 5Zhejiang University, Hangzhou, China, 6Hongik University, Seoul, Korea, Republic of, 7Institute of Medical Physics and Radiation Protection, Mittelhessen University of Applied Sciences, Giessen, Germany, 8Department of Diagnostic and Interventional Radiology, University Hospital Marburg, Philipps University of Marburg, Marburg, Germany, 9Department of Radiology, Massachusetts General Hospital, Boston, MA, United States, 10Harvard/MIT Health Sciences and Technology, Cambridge, MA, United States

Synopsis

Keywords: Data Acquisition, Diffusion/other diffusion imaging techniques

Motivation: High-performance gradients of the Connectome 2.0 system drastically improve diffusion and imaging encoding to enable submillimeter diffusion imaging with high geometric fidelity.

Goal(s): To enable high-resolution, distortion-free diffusion imaging with adequate SNR.

Approach: Distortion-free BUDA-gSlider acquisition was deployed on the Connectome 2.0 system, and was compared against acquisitions using gradients derated to the level of clinical systems.

Results: The Connectome 2.0 system provides improved diffusion-weighted images with higher SNR and geometric fidelity, particularly at submillimeter resolutions.

Impact: High-performance Connectome 2.0 gradients enable high-resolution, distortion-free diffusion-weighted imaging with improved SNR at submillimeter resolutions.

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Abstract

Keywords