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Abstract #4437

MR Elastography Image Reconstruction using Spatio-Temporal Neural Networks-based Regularization

Stefan Martin1, Patrick Schünke 1, Jakob Schattenfroh2, Ingolf Sack2, Christoph Kolbitsch1, and Andreas Kofler1
1Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, 2Charité - Universitätsmedizin Berlin, Berlin, Germany

Synopsis

Keywords: Quantitative Imaging, Elastography

Motivation: MR Elastography (MRE) is a quantitative, noninvasive method to map viscoelastic properties in tissue. We propose a method of advanced image reconstruction to increase resolution and accuracy for fast MRE.

Goal(s): We aim to reduce scan time and, eventually, enable real-time MRE.

Approach: To overcome artifacts resulting from the accelerated data acquisition, we employ a data-driven regularization method. Our approach utilizes a physics-informed convolutional neural network (CNN) that exploits spatio-temporal correlation among the images.

Results: We show that the employed spatio-temporal approach can improve the image reconstruction performance and further outperforms iterative SENSE reconstructions and standard 2D U-Net approaches.

Impact: Our approach allows for the accurate estimation of elastograms from strongly undersampled data, thus allowing a highly reduced scan time. These improvements will eventually benefit clinical practice, making MRE an even more powerful imaging tool.

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Keywords