(ISMRM 2024) Renal Metabolic CEST-MRI Based on Golden-Angle Radial Sampling Under Free Breathing
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Abstract #4452

Renal Metabolic CEST-MRI Based on Golden-Angle Radial Sampling Under Free Breathing

Quan Tao1,2,3, Zelong Chen4, Zhigang Wu5, Kan Deng6, Yizhe Zhang2,3,7, Qianqian Zhang2,3,7, Wenyan Zhang2,3,7, Ting Lin8, and Yanqiu Feng1,2,3,7
1Department of Rehabilitation Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China, 2Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China, 3Guangdong Provincial Engineering Laboratory for Medical Imaging and Diagnostic Technology, Guangzhou, China, 4Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, 5Philips Healthcare, Shenzhen, China, 6Philips Healthcare, Guangzhou, China, 7School of Biomedical Engineering, Southern Medical University, Guangzhou, China, 8Department of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, China

Synopsis

Keywords: CEST / APT / NOE, Kidney

Motivation: Respiration motion may induce artifact in CEST image and the in-accurate quantization of CEST signal.

Goal(s): We aimed to develop clinical motion-insensitive CEST imaging of kidney.

Approach: Here, we used turbo filed echo (TFE) based on golden-angle radial sampling to readout renal CEST image under free breathing of three normal volunteers and also evaluated its effectiveness for motion artifact suppression.

Results: The renal Z-spectrum is float and there is no motion artifact in CEST images. This motion in-sensitive sequence showed high repeatability for renal CEST imaging.

Impact: It may provide a motion in-sensitive CEST imaging sequence for renal imaging in clinical nephropathy patients under free breathing, and improve the accuracy of injury detection.

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Keywords

cestmotionchinarenalmedicalradialgoldenfreeclinicalbreathingsampling