Keywords: CEST / APT / NOE, CEST & MT, NOE
Motivation: Quantitative parameter is required for APT.
Goal(s): Comparing a new quantitative APT parameter APT_T1 (the ratio of APT transfer rate to longitudinal relaxation rate) with MTR_Rex
Approach: APT_T1 was calculated by solving the Bloch equation of multiple pool model. APT_T1 was compared with MTR_Rex in numerical simulation and a clinical case.
Results: MTR_asym was influenced by rNOE and differed from MTR_Rex. On the other hand, although calculation methods of APT_T1 and MTR_Rex were different, APT_T1 approximated MTR_Rex under the condition with strong CEST RF. APT_T1 and MTR_Rex can be used as complementary quantitative APT parameters.
Impact: A new quantitative APT parameter APT_T1 was calculated by solving Bloch equation of multiple pool model. APT_T1 approximated MTR_Rex under the condition with strong and long CEST RF with 100% duty cycle.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords