Meeting Banner
Abstract #4551

Improving Cardiac Phase-Resolved T2*-Mapping of the Murine Heart: Artifact Reduction and Enhanced Accuracy

Shahriar Shalikar1, Oumaima Laghzali1,2, Siqin Liu1, Andreas Pohlmann1, Joao dos Santos Periquito1, Sonia Waiczies1, Thoralf Niendorf1,2,3, and Min-Chi Ku1,2
1Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, 2DZHK (German Centre for Cardiovascular Research), Berlin, Germany, 3Experimental and Clinical Research Center, Charité—Universitätsmedizin Berlin, Berlin, Germany

Synopsis

Keywords: Quantitative Imaging, Animals, Relaxometry, Gradient Moment Nulling, T2*, Retrospective gating, Mouse

Motivation: Rapid blood flow in mice heart imposes severe phase shift error in k-space data, resulting ghosting artifact in the image. These artifacts notably affect the accuracy of myocardial T2* relaxometry, as they introduce variable ghosting artifacts into echo images.

Goal(s): To investigate the effect of Flow Compensation (FC) on myocardial T2*-map acquired by retrospective-gated Multi-Gradient-Echo (MGE) sequence.

Approach: First-order GMN were added to MGE sequence. Retrospective ECG-gating was performed on murine heart.

Results: FC technique can potentially reduce T2* estimation error by mitigating the flow artifact on echo images in mice heart with very fast heart rate.

Impact: First-order Gradient Moment Nulling minimizes image artifacts and enhances the accuracy of myocardial T2* measurements.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords