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Abstract #4574

Compensation of Respiratory Induced Artifacts in the Lumbar Spinal Cord Using a 1D Pre-Acquisition Navigator

Ryan K Robison1,2,3, Kristin P O'Grady2,3,4, Grace Sweeney2, Sandeep Ganji5,6, Brian Johnson7, and Seth Smith2,3,4
1Philips, Nashville, TN, United States, 2Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States, 3Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States, 4Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, 5Philips, Rochester, MN, United States, 6Radiology, Mayo Clinic, Rochester, MN, United States, 7Philips, Cleveland, OH, United States

Synopsis

Keywords: Artifacts, Spinal Cord, Respiration, multi-echo, GRE

Motivation: Respiration induces artifacts and signal loss in axial multi-echo gradient echo imaging of the lumbar spinal cord.

Goal(s): To investigate respiration-induced field shifts in the lumbar cord and to mitigate respiration induced artifacts using a 1D phase navigator.

Approach: A 1D phase navigator, added prior to the multi-echo gradient echo readout, was used to measure and provide compensation for respiration-induced and shot-dependent phase shifts.

Results: The proposed navigator was effective in measuring field shifts and providing a substantial reduction in artifacts in the lumbar spinal cord. Navigator post-processing was simplified compared to that required for a 1D navigator post-readout.

Impact: This work demonstrates, via phantom and in-vivo experiments, self-consistent measurements of respiration-induced field shifts and proposes an approach for their compensation that could be integrated into future spinal cord studies using multi-echo gradient echo acquisitions.

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