Abstract #4575

An UTE-Stack-Of-Spirals Sequence For Biexponential-T1ρ Mapping of Knee Joint

Hector Lise de Moura^1,2, Mahesh Keerthivasan³, Thomas Benkert⁴, and Ravinder Regatte^1,2

¹Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York City, NY, United States, ²Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York City, NY, United States, ³Siemens Medical Solutions USA Inc, Malven, PA, United States, ⁴MR Application Predevelopment, Siemens Healthineers AG, Erlangen, Germany

Synopsis

Keywords: Pulse Sequence Design, Quantitative Imaging

Motivation: Quantitative mapping of the whole knee joint could potentially improve the understanding of how OA initiates and progresses.

Goal(s): To develop an UTE-based spiral sequence capable of quantifying biexponential T_1ρ in knee cartilage, ligaments, tendons, and menisci.

Approach: An UTE stack-of-spirals sequence with a magnetization-preparation module was developed and tested on healthy volunteers at 3T.

Results: The developed UTE-based spiral sequence presented an increased signal-to-noise ratio in T_1ρ- weighted images and a smaller standard deviation in quantitative maps.

Impact: The feasibility of the UTE-based spiral sequence was demonstrated and showed potential for quantifying T_1ρ on short T₂ components in the whole knee joint.

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