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Abstract #4577

Motion robust MR-ARFI using timeseries single-shot spiral acquisition

Morteza Mohammadjavadi1, Kim Butts Pauly2, and Gary H Glover1
1Radiology, Stanford University, Stanford, CA, United States, 2Stanford, Stanford, CA, United States

Synopsis

Keywords: Data Acquisition, Neuro, MR-ARFI

Motivation: 2DFT MR-ARFI methods used to map ultrasound beam profiles can fail with small amounts of head motion because the signal is based on phase shifts from um-sized Acoustic Radiation Force displacement of tissue.

Goal(s): To demonstrate that a single-shot timeseries method is more robust to bulk motion.

Approach: Employing an efficient spiral redout trajectory, we compared the two methods’ ARFI images in a tissue-mimicking phantom undergoing controlled random translations.

Results: The timeseries method demonstrated good quality tissue translation maps, while the 2DFT method failed with motions as small as ~50 microns RMS.

Impact: Our single-shot method may allow routine use of MR-ARFI in humans for guiding US neuromodulation and US-based ablative therapy.

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Keywords