Keywords: Signal Modeling, Oxygenation
Motivation: QQ-CCTV has been validated under 3T to map brain oxygen extraction fraction. Yet its repeatability and reproducibility has not been evaluated under 1.5T.
Goal(s): Assess the repeatability and reproducibility of QQ-CCTV
Approach: QQ-CCTV was performed to calculate brain oxygen extraction from repeated scans under 3T and 1.5T. OEF values are compared between scans using linear regression and Bland-Altman plots.
Results: The OEF values obtained from 3T and 1.5T scans show minimal bias and good correlation. Although under 1.5T the sampled data have lower SNR, QQ-CCTV may benefit from lower characteristic frequency and longer characteristic time.
Impact: QQ-CCTV can be used with mGRE data acquired under 1.5T to map brain oxygen extraction with good repeatability and reproducibility and has the potential to be used clinically.
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