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Abstract #4600

Machine Learning with Multiparametric MRI for preoperative prediction of intraductal component in invasive breast cancer

Lingsong Meng1, Xin Zhao1, Jinxia Guo2, Lin Lu1, Meiying Cheng1, Qingna Xing1, Honglei Shang1, Penghua Zhang1, Yanyong Shen1, and Xiaoan Zhang1
1The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2GE Healthcare MR Research, Beijing, China, Beijing, China

Synopsis

Keywords: Breast, Breast, Machine Learning

Motivation: To predict the presence of an intraductal component (ductal carcinoma in situ, DCIS) in invasive breast cancer (IBC-IC).

Goal(s): To improve the preoperative prediction of IBC-IC.

Approach: This study was to develop and validate a machine-learning algorithm to preoperatively predict IBC-IC using the multiparametric MRI features.

Results: The machine learning model with multiparametric MRI features could provide the individualized probability of IBC-IC and might help to optimize surgical planning for patients with breast cancer before BCS.

Impact: This study developed a prediction model combining a machine-learning algorithm with multiparametric MRI features to preoperatively predict intraductal component in invasive breast cancer, which may be beneficial to the preoperative planning of breast-conserving surgery for early-stage invasive breast cancer.

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