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Abstract #4611

Validating the Use of Breast MRE as a Non-Invasive Diagnostic Technique for Breast Cancer

Akhil Deavela1, Jeffrey R Hawley2, Brandy M Griffith2, Kristin Thompson1, and Arunark Kolipaka1
1The Ohio State University, Columbus, OH, United States, 2Wexner Medical Center, The Ohio State University, Columbus, OH, United States

Synopsis

Keywords: Breast, Elastography

Motivation: While breast tumors can be identified and characterized through biopsy, MR Elastography (MRE) could provide a method of diagnosis with similar sensitivity and specificity while being non-invasive.

Goal(s): Validate the use of MRE against histological grading in biopsy and contrast enhanced MRI breast tumors.

Approach: MRE was performed on patients with known breast tumors to measure the stiffness non-invasively and validate it against biopsy.

Results: Statistically significant correlation was determined between MRE-derived tumor stiffness and histological grade of biopsy.

Impact: The statistically significant association between breast MRE results, a non-invasive method of breast cancer diagnosis, and histological grading, an invasive method, invites the possibility that physicians could diagnose breast cancer non-invasively through further study.

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Keywords