Abstract #4672

End-to-end polar analysis software package for radially acquired fMRI

Mohammad Haft-Javaherian¹, Yalda Zafari-Ghadim², and Abbas Nasiraei-Moghaddam^2,3

¹Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, United States, ²Department of Biomedical Engineering, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran (Islamic Republic of), ³Aerospace & Mechanical Engineering, University of Southern California, Los Angeles, CA, United States

Synopsis

Keywords: Software Tools, Brain

Motivation: Achieving full advantage of radial acquisition and reconstruction by conducting the complete analysis in the polar coordinate system.

Goal(s): Implement a comprehensive end-to-end fMRI analysis software package with a graphical user interface.

Approach: Radially acquired fMRI was reconstructed natively in the polar coordinate system using the Polar Fourier Transform, followed by utilizing preprocessing steps (motion correction and brain extraction) implemented in the polar coordinate system to perform statistical analysis.

Results: The software package performs reconstruction, preprocessing, and statistical analyses of radially acquired fMRI data in the polar coordinate system and is validated using fMRI of 31 healthy subjects.

Impact: This software package facilitates the native polar analysis of radially acquired fMRI that increases the specificity and/or improves the spatial resolution, particularly in task-based brain mapping studies with the region of interest considerably smaller than the field of view

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