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Abstract #4687

Joint q-Space Sampling Optimization and Reconstruction Framework for Accurate and Fast Diffusion Magnetic Resonance Imaging

Jing Yang1,2, Cheng Li1, Wenxin Fan1,2, Juan Zou1,3, Ruoyou Wu1,2,4, Hairong Zheng5, and Shanshan Wang1,4
1Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, 2University of Chinese Academy of Sciences, Beijing, China, 3School of Physics and Optoelectronics, Xiangtan University, xiangtan, China, 4Peng Cheng Laboratory, Shenzhen, China, 5Chinese Academy of Sciences, Shenzhen, China

Synopsis

Keywords: AI/ML Image Reconstruction, Diffusion/other diffusion imaging techniques

Motivation: Current deep learning methods for fast dMRI signal estimation are limited in the accuracy and imaging speed.

Goal(s): Our goal is to enhance the quality of signal estimation and imaging speed for dMRI, by introducing a new deep learning method.

Approach: Our approach fully utilizes the information in both the diffusion gradient domain and spatial domain to design a joint sparse sampling optimization and reconstruction deep learning framework, along with a specifically designed loss function.

Results: The proposed method achieved up to 15x acceleration while maintaining high estimation accuracy, increasing SSIM by 7% compared with other q-space learning approaches.

Impact: The dMRI signal estimation performance of our method is promising, as it incorporates domain knowledge into the deep learning process. This approach improves the acquisition and reconstruction workflow of dMRI, benefiting clinical applicability.

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Keywords