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Abstract #4735

Diagnostic value of GRASP in the differentiation of breast malignancy

Yang Li1, Haifa Liu1, Qi Wang1, Qian Xu1, Mengzhu Wang2, and Hui Liu1
1The Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, China, 2MR Research Collaboration, Siemens Healthineers Ltd, Beijing, China

Synopsis

Keywords: Perfusion, Contrast Mechanisms, breast tumor; dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)

Motivation: Breast MRI plays a vital role in early breast cancer screening, staging, and surgical guidance. The core technology used in breast MRI is DCE-MRI.

Goal(s): This study aims to assess the effectiveness of using the GRASP sequence in distinguishing highly malignant breast lesions.

Approach: We utilized the GRASP sequence, which offers high temporal resolution, to compare and analyze the microvascular characteristics of benign and malignant breast lesions.

Results: We found that Kep was significantly higher in malignant lesions compared to benign lesions, suggesting a potential relationship between the abundant blood supply and high wall permeability observed in malignancies.

Impact: The GRASP dynamic enhancement technique provides both morphological and hemodynamic characteristics of breast lesions, aiding in the differentiation of high-grade malignancies.

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