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Abstract #4737

High-resolution full pancreas water T1 mapping

Elizabeth Huaroc Moquillaza1, Lisa Steinhelfer1, Kilian Weiss2, Yoo Jin Lee3, Jonathan Stelter1, Thomas Amthor3, Peter Koken3, Marcus R. Makowski1, Rickmer Braren1, Mariya Doneva3, and Dimitrios C. Karampinos1
1Institute of Diagnostic and Interventional Radiology, TUM School of Medicine and Health, Department Clinical Medicine, Technical University of Munich, Munich, Germany, 2Philips GmbH Market DACH, Hamburg, Germany, 3Philips Research, Hamburg, Germany

Synopsis

Keywords: Pancreas, Quantitative Imaging, Acquisition & Reconstruction

Motivation: T1 mapping provides valuable insights for the assessment of pancreatic diseases which might be challenging to evaluate if only based on qualitative MRI.

Goal(s): Not only a high-resolution, fast T1 mapping method of the entire pancreas remains a challenge, but also a technique for water T1 mapping since the T1 is biased in the presence of fat.

Approach: This work proposes a high-resolution, rapid, continuous inversion-recovery Look-Locker method combining a spiral read out with Dixon and a dictionary-based processing for water T1 mapping.

Results: The entire pancreas is scanned within 24 slices, distributed in 3 breath-holds of 12s each.

Impact: The present work proposes a high-resolution water T1 mapping methodology of the whole pancreas: 24 slices (2x2x5mm3) in 3 short breath-holds of 12s. The proposed method aims to support the fast assessment of diseases in the entire pancreas.

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Keywords