Meeting Banner
Abstract #4758

3D Diffusion-Prepared FLASH for Prostate MRI Near Metallic Implants

Jeremiah Joseph Hess1,2, Philip Kenneth Lee1, Andrew Anthony Gomella1, Andreas Markus Loening1, and Brian Andrew Hargreaves1,2,3
1Radiology, Stanford University, Stanford, CA, United States, 2Bioengineering, Stanford University, Stanford University, CA, United States, 3Electrical Engineering, Stanford University, Stanford, CA, United States

Synopsis

Keywords: Prostate, New Signal Preparation Schemes

Motivation: Diffusion weighted imaging (DWI) is critical for prostate MRI, but echo planar imaging (EPI) DWI suffers from severe distortion in patients with hip implants or excessive bowel gas, often rendering images unusable.

Goal(s): To develop 3D DWI of the prostate with minimal distortion from nearby metal.

Approach: We compared a diffusion prepared, phase-navigated, fast low-angle shot (FLASH) readout sequence to EPI DWI to assess image quality, distortion correction and diffusion contrast.

Results: Phantom experiments demonstrate the reduced FOV, distortion correction and ADC accuracy. Images in human subjects avoid the severe signal loss and distortion of EPI DWI in the subject with metal.

Impact: We showed that 3D diffusion-prepared FLASH enables DWI where EPI often fails near hip replacements. Increased robustness of prostate imaging protocols to the presence of metal and/or bowel gas may obviate the need for contrast injection in these patients.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords