Abstract #4770

**4D Flow MRI-Derived Hemodynamic Parameters Related to Growth in Acute Type B Aortic Dissections**

Hannah L Cebull¹, Minliang Liu², Hai Dong², John Elefteriades³, Rudy L Gleason⁴, Marina Piccinelli¹, John N Oshinski^1,4, and Bradley G Leshnower⁵

¹Radiology & Imaging Sciences, Emory University, Atlanta, GA, United States, ²The George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, United States, ³Yale University School of Medicine, Aortic Institute at Yale-New Haven Hospital, New Haven, CT, United States, ⁴The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States, ⁵Department of Surgery, Emory University, Atlanta, GA, United States

Synopsis

Keywords: Flow, Velocity & Flow, aorta, aortic dissection, 4D flow MRI

Motivation: In type B aortic dissections (TBAD), surgical outcomes often worsen as the flap stiffens. Earlier intervention (i.e., acute phase) would require prediction of aortic growth to identify high-risk patients, which has not yet been investigated in acute TBADs.

Goal(s): We aimed to identify possible hemodynamic markers of aortic growth from 4D flow MRI data in acute TBAD subjects.

Approach: From the 4D flow data we estimated various hemodynamic metrics.

Results: Peak entry tear velocity, false lumen retrograde flow pre-entry tear, and forward flow post-entry tear were higher in growth cases. We also demonstrate the feasibility of collecting 4D flow MRI from acute patients.

Impact: As the first study focused on in vivo hemodynamics of acute type B aortic dissections (TBAD), we aimed to identify possible metrics for predicting aortic growth. Ultimately, stratifying risk in acute TBAD patients would enable preemptive treatment and improve outcomes.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.