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Abstract #4785

Rapid 3D slab-selective MR elastography using interleaved motion encoding

Donovan Tripp1, Omar Darwish2, Claudia Prieto1,3,4, René Botnar1,3,4,5, Ralph Sinkus1,6, and Radhouene Neji1
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2Siemens Healthineers AG, Erlangen, Germany, 3School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 4Millennium Institute for Intelligent Healthcare Engineering, Santiago, Chile, 5Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 6INSERM U1148, LVTS, University Paris Diderot, Paris, France

Synopsis

Keywords: Elastography, Elastography

Motivation: Most current volumetric 3D MRE sequences are restricted to 2D slice acquisitions, but we propose a novel sequence for rapid 3D slab-selective MRE.

Goal(s): To demonstrate the feasilbility of a 3D slab-selective MRE sequence with an interleaved motion encoding scheme.

Approach: The proposed 3D MRE sequence allows the measurement of different wave offsets and motion encodings for a 3D slab in a single measurement with a constant repetition time, minimising total acquisition time.

Results: We show initial results of the proposed technique in a phantom and for a single breathhold 3D liver MRE in a healthy subject.

Impact: The proposed method can be applied for effiicient 3D high-resolution MRE. Applications include liver fibrosis and inflammation staging, but the sequence may also be used for brain MRE.

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