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Abstract #4819

Value of placental stiffness using virtual magnetic resonance elastography in pregnancies complicated by pre-eclampsia

Jialu Xu1 and Jiejun Cheng1
1Department of Radiology, Shanghai First Maternity and Infant Hospital , Tongji University, Shanghai, China

Synopsis

Keywords: Placenta, Placenta

Motivation: To evaluate virtual magnetic resonance elastography in healthy and preeclamptic(PE) pregnancies.

Goal(s): To compare the stiffness value (μdiff) and apparent diffusion coeffificient (ADC) in healthy and PE pregnancies.

Approach: DWI(b-value of 50 ,200and 800 s/mm2 ) were performed on all pregnant women using a 1.5 T MRI scanner. The value of μdiff and ADC were calculated and compared between groups.

Results: The mean ADC value of the control and PE groups were 1.414±0.228×10-3 mm2/s and 1.737±0.107×10-3 mm2/s, respectively. The mean μdiff value of PE were 5.901±1.757 and 4.618±2.055 kPa, respectively. The area under the curve for μdiff was 0.903 and ADC was 0.796, respectively.

Impact: Placental μdiff value was found to be more reliable than ADC in differentiating between normal and preeclampsia placentas.

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