Abstract #4835

Elastic modulus of acetabular labrum correlates with UTE apparent spin-spin (T2*) and spin-lattice (T1) magnetic resonance relaxation times

Dina Moazamian¹, Takehito Hananouchi^2,3, Hamidreza Shaterian Mohammadi¹, Arya Suprana¹, Alireza Tayarani⁴, Erik W Dorthe³, Darryl W D’Lima³, Yajun Ma⁵, and Saeed Jerban⁵

¹Radiology, University of California San Diego, San Diego, CA, United States, ²Academia-Government-Industry Collaboration, Office of Research and Academia-Government-Community Collaboration Hiroshima University, Hiroshima, Japan, ³Orthopedic, Shiley Center for Orthopedic Research and Education at Scripps Clinic, San Diego, CA, United States, ⁴Pathology, University of California San Diego, San Diego, CA, United States, ⁵Radiology, Radiology, University of California San Diego, San Diego, CA, United States, San Diego, CA, United States

Synopsis

Keywords: High-Field MRI, Cartilage, Acetabular Labrum, UTE

Motivation: The acetabulum labrum plays a critical role in the hip function. Medical imaging techniques for detecting labral degeneration may help improve our knowledge of its role in hip osteoarthritis (OA).

Goal(s): This study aimed to explore the correlation between the mechanical properties of the acetabulum labrum and MRI properties.

Approach: The correlations of UTE-T2* and -T1 sequences with the tensile elastic modulus of human acetabular labrum specimens have been investigated.

Results: There was a significant correlation between quantitative UTE-T2*, and UTE-T1 techniques and the mechanical properties of the labrum.

Impact: UTE-T2* and -T1 sequences showed the potential to evaluate acetabulum labrum mechanical assessment, which is needed to improve labrum degeneration detection and monitoring, a primary unmet need in areas where hip osteoarthritis is common and conventional MRI is being implemented.

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