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Abstract #4842

Initial experience of proton short echo MR spectroscopy of human brain at 5T

Hongxia Lei1,2, Linfei Wen1, Bin Deng3, Aiguo Xue1, and Chaohong Wang1
1United-Imaging Healthcare, Shanghai, China, 2Wuhan United-Imaging Life Science Instrument Ltd Co., Wuhan, China, 3United-Imaging Healthcare, Shenzhen, China

Synopsis

Keywords: High-Field MRI, Metabolism, spectroscopy

Motivation: Proton short echo (TE≤10ms) MR spectroscopy of human brain at high magnetic fields (≥3T) provides abundant metabolic information beyond MR images, but remains challenging for routine clinical usages beyond 3T.

Goal(s): To evaluate feasibility and assess quality of proton ultrashort echo (i.e.10ms) MR spectroscopy of human brain on a clinical, whole-body 5T MRI system.

Approach: Stimulated echo acquisition mode (STEAM) spectra with TE=10ms were obtained in human brain at 3T and 5T.

Results: The feasibility of short echo MR spectroscopy of human brain at 5T was first demonstrated. The spectral quality is substantially improved when compared to 3T.

Impact: The quality of short echo MR spectra at 5T could be reached without exceeding the SAR and thus may offer additional metabolite information for large amount of clinical diagnostic applications.

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Keywords