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Abstract #4853

MRI-based prediction of cerebral palsy risk in infants aged 6 months to 2 years: a deep learning approach

Zhen Jia1,2,3, Tingting Huang2,3, Man Li4, Yitong Bian2,3, Xianjun Li2,3, Feng Shi4, and Jian Yang1,2,3
1School of Future Technology, Xi'an Jiaotong University, Xi'an, China, 2Department of Radiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China, 3Shaanxi Engineering Research Center of Computational Imaging and Medical Intelligence, Xi'an, China, 4Department of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China

Synopsis

Keywords: Diagnosis/Prediction, Brain, Cerebral Palsy

Motivation: Early prediction of cerebral palsy (CP) in infants plays a pivotal role in facilitating tailored rehabilitation treatment.

Goal(s): We hope to achieve early prediction of CP in infants aged 6 months to 2 years old based on MRI and deep learning technology.

Approach: We introduce a novel neural network model, known as the "Cerebral Palsy Brain Constraint Residual Network" (CPBC-Resnet), for the automatic prediction of CP risk based on MRI data.

Results: The CPBC-Resnet model exhibits an impressive receiver operating characteristic area under the curve (AUC) of 0.9521, achieving a sensitivity of 94.12% and a specificity of 100%.

Impact: This study streamlines cerebral palsy (CP) imaging diagnostics, reducing physician training costs, and expanding the reach of CP diagnostic technology. It promotes early CP diagnosis and intervention, particularly in areas with underdeveloped medical standards, contributing to overall child health improvement.

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