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Abstract #4855

Classification of Grade II and III Astrocytomas for Multi-modal MRI using Deep Volumetric Attention Networks.

Hamail Ayaz1, Oladosu Oyebisi Oladimeji1, David Tormey2, Ian McLoughlin3, and Saritha Unnikirishnan1
1Computing and Electronics, Atlantic Technological University Sligo, Sligo, Ireland, 2Mechanical & Electronic Engineering, Atlantic Technological University Sligo, Sligo, Ireland, 3Computer Science and Applied Physic, Atlantic Technological University Sligo, Galway, Ireland

Synopsis

Keywords: Diagnosis/Prediction, Brain, Volumetric Attention Network, Deep Learning, Astrocytomas, Glioma, Classification

Motivation: Diagnosis and grading of astrocytomas tumour present considerable challenges. Manual grading is time-consuming and error prone. Preoperative MRIs are a useful, yet deep learning presents challenges due to computing limitations and complex architecture.

Goal(s): Study introduces novel multimodal MRI classification for grade II and III astrocytomas, aiming to improve accuracy, reduce complexity, and address interclass homogeneity via attention mechanism.

Approach: Single slice from eight MRI modalities forms a three-dimensional cube. Normalized, iPCA processed, and passed to deep model with volumetric attention network.

Results: The DVA using advanced and traditional MRI information outperforms existing models achieving an overall accuracy of 77% using five-fold cross-validation.

Impact: The proposed multimodal MRI classification approach enhances astrocytoma diagnosis and grading. The deep volumetric attention model improves accuracy, reduces model complexity, and holds potential for trustworthiness impacts in clinical practice.

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Keywords