Keywords: Arterial Spin Labelling, Perfusion, Pediatrics
Motivation: Moyamoya is a progressive cerebrovascular disorder affecting hemodynamics and the disease often begins during childhood. However, the non-invasive assessments of hemodynamics in pediatric Moyamoya patients remain an open question.
Goal(s): Investigate the CBF change before and after revascularization in pediatric Moyamoya patients.
Approach: CBF in 42 patients was measured using arterial spin labeling on a 3T MRI 1 week before and within 2 weeks after revascularization. CBF in regions affected by vasculopathy was compared before and after revascularization.
Results: CBF in regions affected by vasculopathy increased significantly after revascularization.
Impact: ASL can be utilized to evaluate CBF in pediatric Moyamoya patients before and after direct revascularization.
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