Abstract #4914

Good agreement of turbulent kinetic energy assessment by compressed sensing-accelerated 4D flow MRI in aortic stenosis patients

Sungho Park^1,2,3, Ning Jin⁴, Dongyeop Han⁵, Bae Young Lee⁶, Minseong Kwon³, Jeong-Eun Yi⁷, and Hyungkyu Huh³

¹Department of Radiology, Children's Hospital Colorado, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, ²Institute of Medical Devices, Kangwon National University, Chuncheon, Korea, Republic of, ³Medical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Korea, Republic of, ⁴Cardiovascular MR R&D, Siemens Medical Solutions, Cleveland, OH, United States, ⁵Siemens Healthineers Ltd., Seoul, Korea, Republic of, ⁶Department of Radiology, Eunpyeong St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of, ⁷Division of Cardiology, Department of Internal Medicine, Eunpyeong St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of

Synopsis

Keywords: Flow, Data Analysis, 4D flow MRI, Compressed sensing

Motivation: Compressed sensing (CS) acceleration has improved the clinical applicability of 4D flow MRI. However, but no studies have investigated turbulent kinetic energy (TKE) assessment using CS-accelerated 4D flow MRI.

Goal(s): This study aims to validate TKE assessment in CS 4D flow MRI compared to conventional 4D flow MRI.

Approach: The effect of CS acceleration on TKE assessment was evaluated by in vitro coarctation model. In addition, TKE assessment was further validated in healthy subjects and aortic stenosis (AS) patients.

Results: TKE parameters had good agreement in AS patients at the ascending aorta, while healthy subjects had significant differences.

Impact: TKE estimation has been limited due to asymmetric velocity encoding scheme, requiring additional MR scans. This study firstly validates the reliability of TKE using CS 4D flow with reduced scan time in AS patients.

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