Keywords: Neurofluids, Neurofluids
Motivation: Recent studies highlight the significant impact of arterial pulsation on CSF movements in animal studies, but direct comparison in awake humans is still limited.
Goal(s): This study aims to concurrently measure CSF and CBF, excluding the influence of breathing, to analyze their correlation. Additionally, it investigates changes in CSF movement during the motor task.
Approach: Simultaneously measuring CBF and CSF by applying pCASL, and comparing how they change during breath-holding and motor tasks.
Results: During breath-holding, we observed a positive correlation between CBF and CSF. Furthermore, we confirmed reduced CSF inflow during the motor task compared to the resting state.
Impact: The relationship between CSF movement and CBF was analyzed during breath-holding and motor tasks in humans for the first time. This study offers a new way to study CBF and CSF movement, providing a better understanding of CBF-CSF physiology.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords