Abstract #5013

Improvement of motion-related misalignments in dynamic contrast-enhanced breast MRI using advanced 3D fast elastic image registration

Mana Kato¹, Masami Yoneyama², Michinobu Nagao³, Yasutomo Katumata², Javier Sánchez-González⁴, Jaladhar Neelavalli⁵, Johannes M Peeters⁶, Sven Kabus⁷, Kazuo Kodaira¹, Takumi Ogawa¹, Yutaka Hamatani¹, Isao Shiina¹, Yasuhiro Goto¹, Yasuyuki Morita¹, and Shuji Sakai³

¹Department of Radiological Services, Tokyo Women's Medical University, Tokyo, Japan, ²Philips Japan, Tokyo, Japan, ³Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan, ⁴Philips Healthcare Iberia, Madrid, Spain, ⁵Philips India, Bangalore, India, ⁶Philips Healthcare, Best, Netherlands, ⁷Philips Research, Humburg, Germany

Synopsis

Keywords: Breast, Breast

Motivation: Motion and breathing artifacts in DCE breast MRI can cause misalignment among each dynamic, resulting in inaccurate tumor assessment.

Goal(s): Our goal was to demonstrate the feasibility of advanced fast elastic image registration (FEIR) for correction of misalignment in breast DCE MRI.

Approach: FEIR was applied and evaluated in 11 patients who underwent breast DCE examinations.

Results: Advanced FEIR clearly improved misalignments among dynamic scans and provided improved accuracy of time intensity curves (TICs).

Impact: FEIR improves motion related misalignments among respective dynamic scans in DCE breast MRI, it could improve the TICs more accurately.

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