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Abstract #5051

The application of 3D-ZTE technique in ex vivo ankle cortical bone MRI of adolescent pigs: A comparison with CT examination

Wanjing Bai1, Xian Xiong1, Yaqi Li1, Lingjun Jiang1, Xiyang Song1, Xiaoxuan Li1, and Huilou Liang2
1West China Second University Hospital, Sichuan University, Chengdu, China, 2GE HealthCare MR Research, Beijing, China

Synopsis

Keywords: Bone, MSK, ZTE

Motivation: Exploring non-ionizing radiation alternatives to CT examination for diagnosing bone diseases in children is clinically desirable.

Goal(s): To compare the visualization of the bone cortex around ankle joints of adolescent pig between 3D-ZTE MRI and CT techniques.

Approach: A total of 12 specimens were subjected to both 3D-ZTE MRI and CT examination. The thicknesses of bone cortex were measured and compared between MRI and CT images.

Results: There was no significant difference in the thicknesses of bone cortex in the inner and outer sides of tibia, fibula, and talus between 3D-ZTE and CT.

Impact: 3D-ZTE technique can obtain CT-like images that accurately measure the thickness of bone cortex without ionizing radiation. This technique holds the potential for clinical applications in children with bone diseases, providing a safe alternative to traditional CT imaging.

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