Abstract #5172

Altered Functional Connectivity of the Olfactory Cortex in Post-COVID-19 Brain Network

Ruoxi Lu^1,2, Gianpaolo Del Mauro², Yan Guo¹, Xinyu Liang¹, Jianyu Li¹, Yanting Zheng³, Yiran Li², Yujie Liu³, Ze Wang², and Shijun Qiu³

¹First clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China, ²Department of Diagnostic Radiology & Nuclear Medicine, University of Maryland,Baltimore, Baltiomore, MD, United States, ³The Department of Radiology, The first Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

Synopsis

Keywords:

Motivation: To investigate the persistent effects on the brain following recovery from COVID-19.

Goal(s): To examine differences in brain’s functional connectivity between post-COVID-19 subjects and healthy controls.

Approach: To use resting-state fMRI data to identify brain functional networks.

Results: Post-COVID subjects exhibited higher functional connectivity in a brain network including the left olfactory cortex as the main hub connected to other brain regions.

Impact: We observed that post-COVID-19 subjects continue to exhibit significant anomalies in the olfactory cortex of the brain. These results support previous findings and highlight the relevance of research from a fMRI perspective for investigating the effects on brain of COVID-19.

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