Motivation: Cardiac diffusion tensor imaging (cDTI) enables the characterization of the myocardial microstructural environment. However, B0 inhomogeneity around the heart can lead to EPI distortion and signal loss in cDTI.
Goal(s): To investigate the feasibility of using FSL TOPUP for EPI Distortion Correction in cDTI.
Approach: This proposed approach could be seamlessly integrated into cDTI postprocessing, significantly improving the accuracy and reproducibility of cDTI, particularly when researchers are analyzing metrics alongside other cardiac image parameters.
Results: The FSL TOPUP method could correct EPI distortion in both diffusion-weighted images (b0 and b400), following which kinds of cDTI metrics are reconstructed successfully after the correction.
Impact: The FSL TOPUP algorithm has been successfully integrated into the cDTI postprocessing in order to correct EPI distortion effectively.
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