Abstract #5187

MRI-based methods for measuring foot perfusion

Malene Bisgaard^1,2,3, Kim Christian Houlind^2,4, Anne Dorte Blankholm^5,6, Steffen Ringgaard⁷, Johnny Christensen³, and Helle Preht^1,3,8

¹Health Sciences Research Centre, UCL University College Odense, Odense, Denmark, ²Regional Health Research,, University of Southern Denmark, Odense, Denmark, ³Radiology, Lillebealt Hospital, Kolding, Denmark, ⁴Vascular Surgery, Lillebealt Hospital, Kolding, Denmark, ⁵Radiology, Aarhus University Hospital,, Aarhus, Denmark, ⁶Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark, ⁷MR Research Center, Aarhus University, Aarhus, Denmark, ⁸Regional Health Research, University of Southern Denmark, Odense, Denmark

Synopsis

Motivation: For patients with peripheral artery disease knowing the perfusion in different areas of the foot might have clinical relevance when treating ischemia.

Goal(s): The aim was to measure the reliability of five different MR sequences with quantitative parameters for measuring perfusion when imaging the foot.

Approach: We used a cuff induced ischemia protocol in a test/retest study of 16 healthy volunteers

Results: Flow-sensitive Alternating Inversion Recovery pulsed arterial spin labelling (FAIR) and Blood Oxygenation Level-Dependent (BOLD) sequences had high reliability and were able to distinguish between occluded blood flow and hyperactive response flow

Impact: Reliability test of five different MR sequences for quantitative perfusion measurements in the foot.

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