Abstract #0027

High-resolution 0.16-mm time-of-flight angiography at 7 T with volumetric navigators for prospective motion correction

Daniel Haenelt^1,2, Jonathan R Polimeni^1,2,3, Yulin Chang⁴, Saskia Bollmann⁵, Daniel EP Gomez^1,2,6, Shahrokh Abbasi-Rad^1,2, Andre Van der Kouwe^1,2, and Robert Frost^1,2

¹Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ²Department of Radiology, Harvard Medical School, Boston, MA, United States, ³Harvard-MIT Program in Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States, ⁴Siemens Medical Solutions USA Inc., Malvern, PA, United States, ⁵School of Electrical Engineering and Computer Science, The University of Queensland, Brisbane, Australia, ⁶Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States

Synopsis

Keywords: Motion Correction, Motion Correction, High-Field MRI

Motivation: High-resolution time-of-flight (TOF) magnetic resonance angiography (MRA) is needed for imaging the cerebral vasculature at the mesoscopic scale but is challenged by involuntary head movements during image acquisition.

Goal(s): This study tests whether whole-brain volumetric navigators (vNavs), based on 3D-EPI, can be used for prospective motion correction (PMC) of thin-slab TOF acquisitions at 7T.

Approach: Interactions between vNavs and TOF sequence modules are examined, and the performance of PMC is investigated under different head motion conditions.

Results: While results show that vNavs affect TOF signal, vNav motion correction enables the robust imaging of small vessels.

Impact: We show that slab-selective isotropic 0.16-mm TOF-MRA is feasible with whole-brain volumetric navigators for prospective head motion correction, enabling robust in vivo imaging of the human vasculature at an unprecedented scale.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.