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Abstract #0033

Motion- and field-robust ultra-high-resolution whole-brain imaging enabled by servo navigation

Matthias Serger1, Ruediger Stirnberg1, Philipp Ehses1, Malte Riedel2, Thomas Ulrich3, Maxim Zaitsev4, Nicolas Boulant5, Klaas Pruessmann2, and Tony Stoecker1,6
1German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, 2Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Zurich, Switzerland, 3GyroTools LLC, Zurich, Switzerland, 4Division of Medical Physics, Department of Radiology, University Medical Center Freiburg, Freiburg, Germany, 5Neurospin, CEA, Paris, France, 6Department of Physics and Astronomy, University of Bonn, Bonn, Germany

Synopsis

Keywords: Motion Correction, Motion Correction

Motivation: Even subtle involuntary motion can degrade image quality in ultra-high-resolution imaging due to long acquisition times.

Goal(s): To reduce motion and dynamic field induced artifacts in ultra-high-resolution T2*-weighted imaging (0.25mm³) using servo navigators for prospective correction at 7T.

Approach: Servo navigators were integrated into a segmented 3D-EPI sequence to correct motion and field variations. Involuntary motion experiments were conducted, and minimum-intensity projections were used to assess the effect of prospective correction on fine details in brain anatomy.

Results: Servo navigators provide motion and field estimates with sufficiently high precision and successfully mitigate artifacts in ultra-high-resolution MRI, enabling the investigation of submillimeter brain structures.

Impact: Improvements in visibility of small vessels demonstrate the capability of servo navigators to correct for small motions and field changes during ultra-high-resolution T2*-weighted whole-brain imaging (0.25mm isotropic) using 3D-EPI.

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Keywords