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Abstract #0048

Vessel wall imaging-dedicated deep learning (VWI-DL): Toward a 5-min clinically robust MR protocol

Pengcheng Wang1,2, Junzhou Chen1,3, Zhenjia Wang4, Nasim Sheikh-Bahaei1, Steven Yong Cen1, Qi Yang5, William Mack6, and Zhaoyang Fan1,2
1Department of Radiology, University of Southern California, Los Angeles, CA, United States, 2Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, United States, 3Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States, 4Department of Radiology, Anzhen Hospital, Beijing, China, 5Department of Radiology, Chaoyang Hospital, Beijing, China, 6Department of Neurological Surgery, University of Southern California, Los Angeles, CA, United States

Synopsis

Keywords: Vascular/Vessel Wall, Vessel Wall, Imaging acceleration, whole-brain vessel wall imaging

Motivation: Long scan times (8–12 minutes) in whole-brain MR vessel wall imaging (VWI) cause patient discomfort and motion artifacts, limiting clinical utilization. Faster VWI with preserved image quality is highly desirable.

Goal(s): To develop a VWI-dedicated deep learning model to substantially accelerate data acquisition without compromising image quality.

Approach: We developed a multi-view deep learning model using SwinIR as the backbone, trained it on 12-min VWI raw data, and used a voting mechanism across views to enhance consistency. Both retrospective and prospective testing were performed.

Results: The model reduced scan time to <6 minutes with PSNR and SSIM improvements of 9.69 and 0.28.

Impact: The VWI-dedicated deep learning model enables faster data acquisition with preserved image quality compared to standard clinical protocols, which may enhance VWI’s robustness and clinical throughput and thus promote its widespread clinical adoption.

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Keywords